C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 9/80 (2006.01) C07C 213/00 (2006.01) C07C 215/42 (2006.01) C07D 209/52 (2006.01) C12N 1/20 (2006.01) C12P 13/00 (2006.01) C12P 13/02 (2006.01) C12P 41/00 (2006.01)
Patent
CA 2253977
The invention relates to novel micro-organisms which are capable of utilising cyclopentene derivatives of the general formula (VII), in which R1 is C1-C4-alkyl, C1-C4-alkoxy, aryl or aryloxy, as the only nitrogen source, as the only carbon source or as the only carbon and oxygen source. The invention also relates to novel enzymes which hydrolyse the cyclopentene derivatives of the general formula (VII). Furthermore, the invention relates to a novel process for the preparation of (1R,4S) or (1S,4R)-1-amino-4(hydroxymethyl)-2-cyclopentene of the formulas (I) and (II) and/or of a (1S,4R) or (1R,4S)-amino-alcohol derivative of the general formulas (III) and (IV), in which R1 has the above meaning.
L'invention concerne de nouveaux micro-organismes capables de valoriser, en tant que seule source d'azote, seule source de carbone ou seule source d'azote et de carbone, des dérivés de cyclopentène de formule (VII), où R<1> représente alkyle C1-C4, alcoxy C1-C4, aryle ou aryloxy. L'invention concerne également de nouvelles enzymes qui hydrolysent les dérivés de cyclopentène de formule (VII). L'invention concerne en outre un nouveau procédé de préparation de (1R,4S)- ou (1S,4R)-1-amino-4-(hydroxyméthyl)-2-cyclopentène de formule (I), (II) et/ou d'un dérivé de (1S,4R)- ou (1R,4S)-aminoalcool de formule générale (III), (IV), où R<1> a la signification mentionnée ci-dessus.
Bernegger-Egli Christine
Birch Olwen M.
Bossard Pierre
Brieden Walter
Brux Frank
G. Ronald Bell & Associates
Lonza Ag
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