Use of dipyridamole or mopidamol in the manufacture of a...

A - Human Necessities – 61 – K

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A61K 31/505 (2006.01) A61K 31/519 (2006.01) A61K 31/616 (2006.01) A61K 45/06 (2006.01) A61P 7/02 (2006.01)

Patent

CA 2387486

A method of treatment of the human or non-human animal body for treating fibrin-dependent microcirculation dis-orders is disclosed, for example microcirculation disorders caused by metabolic diseases, inflammatory reactions or autoimmune diseases, furthermore peripheral microcirculation disorders or microcirculation disorders associated with increased cell fragmenta-tion, which method comprises administering to a human or non-human animal body in need of such treatment an effective amount of a pharmaceutical composition containing a pyrimido-pyrimidine selected from dipyridamole, mopidamol and the pharmaceutically acceptable salts thereof, and the use of said pyrimido-pyrimidine for the manufacture of a corresponding pharmaceutical composi-tion.

L'invention concerne un traitement de médecine animale ou vétérinaire dirigé contre les troubles de la microcirculation liés à la fibrine, notamment en raison de maladies du métabolisme, mais aussi contre des réactions inflammatoires ou des maladies auto-immunes, ainsi que des troubles de la microcirculation périphérique ou associés à une augmentation de la fragmentation cellulaire. A cet effet, on administre au sujet une quantité suffisante d'une composition pharmaceutique contenant une pyrimido-pyrimidine choisie parmi les dipyridamole et mopidamol et certains de leurs sels pharmaceutiquement admis. L'invention concerne également l'utilisation de cette pyrimido-pyrimidine pour la fabrication d'une composition pharmaceutique correspondante.

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