A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/26 (2006.01) C12Q 1/00 (2006.01) G01N 33/483 (2006.01)
Patent
CA 2236519
The invention relates to glucagon-related peptides and their use for the prevention or treatment of disorders involving the large intestine. In particular, it has now been demonstrated that GLP-2 and peptidic agonists of GLP-2 can cause proliferation of the tissue of large intestine. Thus, the invention provides methods of proliferating the large intestine in a subject in need thereof. Further, the methods of the invention are useful to treat or prevent inflammatory conditions of the large intestine, including inflammatory bowel diseases.
L'invention a trait à des peptides semblables au glucagon et à leur utilisation pour prévenir ou traiter des troubles du gros intestin. En particulier, il a désormais été démontré que le GLP-2 et des agonistes peptidiques du GLP-2 peuvent causer la prolifération du tissu du gros intestin. Ainsi, l'invention fournit des méthodes de prolifération du tissu du gros intestin chez un sujet qui en a besoin. En outre, les méthodes dévoilées sont utiles pour traiter ou prévenir l'inflammation du gros intestin, y compris les maladies intestinales inflammatoires.
1149336 Ontario Inc.
Osler Hoskin & Harcourt Llp
LandOfFree
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