Methods and compositions useful for inhibition of angiogenesis

Details Methods and compositions useful for inhibition of angiogenesis Methods and compositions useful for inhibition of angiogenesis

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61K 38/10 (2006.01) A61K 38/12 (2006.01) C07K 14/705 (2006.01) C07K 14/78 (2006.01) C07K 16/28 (2006.01) C07K 16/30 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2184493

The present invention describes methods for inhibiting angiogenesis in tissues using vitronectin .alpha.v.beta.3 antagonists, and particularly for inhibiting angiogenesis in inflamed tissues and in tumor tissues and metastases using therapeutic compositions containing .alpha.v.beta.3 antagonists.

La présente invention décrit un procédé d'inhibition de l'angiogenèse au niveau des tissus à l'aide d'antagonistes de la vitronectrine .alpha.¿v?.beta.¿3?, et permettant plus particulièrement l'inhibition de l'angiogenèse des tissus enflammés ainsi que des tissus tumoraux et des métastases, lequel procédé fait appel à des compositions thérapeutiques contenant des antagonistes de .alpha.¿v?.beta.¿3?.

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