Treatment of atherosclerotic disease

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/5383 (2006.01) A61K 31/395 (2006.01) A61P 9/10 (2006.01)

Patent

CA 2644118

The invention features a method of inhibiting the progression of intima- media thickening, or reducing the intima-media thickness (IMT) in arteries in a patient in need thereof by administering to the patient a rifamycin in an amount effective to inhibit the progression of intima-media thickening, or reduce the IMT. The invention also features a method for treating or preventing cerebral vascular disease in a patient in need thereof by administering to the patient a rifamycin in an amount effective to treat the cerebral vascular disease in the patient.

La présente invention concerne un procédé visant à inhiber la progression de l'épaisseur de l'intima-média ou à réduire l'épaisseur de l'intima-média (IMT) dans les artères d'un patient en ayant besoin. Le procédé consiste à administrer au patient de la rifamycine dans une quantité efficace pour inhiber la progression de l'épaisseur de l'intima-média ou pour réduire l'IMT. L'invention concerne également un procédé de traitement ou de prévention d'une maladie vasculaire cérébrale chez un patient en ayant besoin, procédé basé sur l'administration de rifamycine au patient dans une quantité efficace pour traiter la maladie vasculaire cérébrale chez le patient.

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