Piperididinyl and n-amidinopiperidinyl derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 211/68 (2006.01) A01N 43/40 (2006.01) A61K 31/44 (2006.01) A61K 31/4406 (2006.01) A61K 31/4409 (2006.01) A61K 31/445 (2006.01) A61K 31/4462 (2006.01) A61K 31/4465 (2006.01) A61K 31/454 (2006.01) A61K 31/4545 (2006.01) A61K 31/47 (2006.01) A61P 7/02 (2006.01) A61P 9/10 (2006.01) C07D 211/00 (2006.01) C07D 211/26 (2006.01) C07D 211/28 (2006.01) C07D 211/32 (2006.01) C07D 211/34 (2006.01) C07D 211/70 (2006.01) C07D 233/64 (2006.01) C07D 401/12 (2006.01) C07D 409/04 (2006.01) C07D 409/14 (2006.01)

Patent

CA 2325471

This invention is directed to a compound of formula (I) which is useful for inhibiting the activity of Factor Xa, by combining said compound with a composition containing Factor Xa. The present invention is also directed to compositions containing compounds of formula (I), methods for their preparation, their use, such as in inhibiting the formation of thrombin or for treating a patient suffering from, or subject to, a disease state associated with a physiologically detrimental excess amount of thrombin.

La présente invention concerne un composé de la formule (I) s'utilisant pour inhiber l'activité du facteur Xa, par combinaison de ce composé avec une composition contenant un facteur Xa. La présente invention concerne également des compositions contenant les composés de la formule (I), leurs procédés de préparation, leur utilisation, comme pour l'inhibition de la formation de thrombine ou pour le traitement d'un patient souffrant d'une affection associée à un excès physiologiquement nuisible de thrombine.

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