Methods and compositions for diagnosing, monitoring and...

C - Chemistry – Metallurgy – 07 – K

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167/37, 195/1.11

C07K 16/18 (2006.01) A61K 47/48 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2001373

-28- ABSTRACT Methods of and compositions for early diagnosis, monitoring and treatment of osteoarthritis using monoclonal antibodies which specifically recog- nize antigenic determinants on atypical chondroitin sulfate/dermatan sulfate glycosaminoglycan chains in body tissues and fluids, which determinants are markers of osteoarthritis.

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