Fibrate compositions containing a surfactant mixture of...

A - Human Necessities – 61 – K

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A61K 31/216 (2006.01)

Patent

CA 2600407

The invention provides at least a composition for the treatment of elevated levels of triglycerides, comprising a therapeutically effective amount of a fibrate drug, preferably fenofibrate, intimately associated with a surfactant mixture, preferably a mixture comprising PGE 6000 and poloxamer 407. The invention also provides a method for the treatment of elevated levels of triglycerides in a subject, comprising administering to the subject the composition.

La présente invention concerne au moins une composition destinée au traitement de niveaux élevés de triglycérides, laquelle composition contient une quantité thérapeutiquement efficace d'un fibrate, de préférence un fenofibrate, associé à un mélange tensioactif, de préférence, un mélange qui contient du PGE 6000 et un poloxamère 407. La présente invention concerne également une méthode permettant de traiter des niveaux élevés de triglycérides chez un sujet, laquelle méthode consiste à administrer la composition susmentionnée au sujet.

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