Transdermal vaccine delivery device having coated...

Details Transdermal vaccine delivery device having coated... Transdermal vaccine delivery device having coated...

A - Human Necessities

61

M

A61M 37/00 (2006.01) A61B 17/20 (2006.01) A61K 9/00 (2006.01) A61K 39/00 (2006.01) A61K 39/145 (2006.01)

Patent

CA 2495270

A device and method are provided for percutaneous transdermal delivery of a immunologically active agent. The agent is mixed with appropriate surfactants and dissolved in water to form an aqueous coating solution having the appropriate concentration for coating extremely tiny skin piercing elements. The coating solution is applied to the skin piercing elements using known coating techniques and then dried. The device is applied to the skin of a living animal, causing the microprotrusions to pierce the stratum corneum and deliver a immunologically effective dose of the immunologically active agent to the animal.

L'invention concerne un dispositif et un procédé d'administration transdermique percutanée d'un agent actif d'un point de vue immunologique. L'agent est mélangé à des agents de surface appropriés et dissout dans l'eau afin de former une solution de revêtement aqueuse présentant une concentration appropriée pour revêtir des éléments de perçage de la peau minuscules. Cette solution de revêtement est appliquée sur les éléments de perçage de la peau au moyen des techniques de revêtement connues, puis séchée. Ce dispositif est appliqué sur la peau d'un animal vivant, ce qui pousse les micro-protubérances à percer la couche cornée et entraîne l'administration d'une dose efficace d'un point de vue immunologique de l'agent actif d'un point de vue immunologique à l'animal.

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