A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) A61K 38/00 (2006.01) A61K 38/16 (2006.01) A61K 39/00 (2006.01) C07K 16/30 (2006.01) G01N 33/53 (2006.01) G01N 33/574 (2006.01)
Patent
CA 2367256
This invention relates, e.g., to colligin/Hsp47 molecules which are expressed on the surface of carcinoma cells and to the use of such expressed molecules as targets for, e.g., therapeutic agents or imaging agents. The invention also relates to peptides which bind specifically to external domains of such surface-localized Hsp47 molecules.
La présente invention concerne essentiellement, d'une part des molécules de colligin/Hsp47 qui s'expriment sur la surface des cellules des carcinomes, et d'autre part l'utilisation de celles molécules d'expression comme cibles essentiellement d'agents thérapeutiques ou d'imagerie. L'invention concerne également des peptides qui se lient spécifiquement aux domaines externes de telles molécules de colligin/Hsp47 à localisation superficielle.
Parlee Mclaws Llp
University Of Maryland Baltimore
LandOfFree
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