Methods of therapy and diagnosis using targeting of cells...

Details Methods of therapy and diagnosis using targeting of cells... Methods of therapy and diagnosis using targeting of cells...

A - Human Necessities

61

K

A61K 39/38 (2006.01) A61K 48/00 (2006.01) C07H 21/04 (2006.01) C07K 14/705 (2006.01) C07K 16/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2507156

Certain cells are capable of expressing LAX RNA. Targeting using LAX polypeptides, nucleic acids encoding for LAX polypeptides and anti-LAX antibodies, peptides and small molecules provides a method of killing or inhibiting the growth of cells that express the LAX protein. Methods of therapy and diagnosis of disorders associated with LAX protein-expressing cells are described.

L'invention concerne certaines cellules capables d'exprimer l'ARN LAX. Le ciblage à l'aide de polypeptides LAX, d'acides nucléiques codant ces polypeptides et d'anticorps anti-LAX, de peptides et de petites molécules est utilisé dans un procédé d'élimination ou d'inhibition de la croissance de cellules exprimant la protéine LAX. Cette invention concerne également des procédés de traitement et de diagnostic de troubles associés à des cellules exprimant la protéine LAX.

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