C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/63 (2006.01) A61K 48/00 (2006.01) C12N 9/22 (2006.01) C12N 15/55 (2006.01) C12N 15/861 (2006.01) C12N 15/90 (2006.01)
Patent
CA 2373121
The present invention provides non-integrating vectors, preferably non- integrating viral vectors, that include a transposon, preferably a transposon and nucleotide sequences encoding a transposase, and most preferably a transposon, nucleotide sequences encoding a transposase, and nucleotide sequences encoding a polypeptide that regulates expression of the transposase. Also provided are methods of using the non-integrating vectors.
La présente invention concerne des vecteurs non intégrateurs, de préférence des vecteurs viraux non intégrateurs, qui incluent un transposon, de préférence un transposon et des séquences nucléotidiques codant un transposon, ou mieux, un transposon, des séquences nucléotidiques codant un transposon et des séquences nucléotidiques codant un polypeptide, lequel régule l'expression de la transposase. L'invention concerne en outre des méthode d'utilisation desdits vecteurs non intégrateurs.
Aguilar-Cordova Estuardo
Mcivor R. Scott
Baylor College Of Medicine
Regents Of The University Of Minnesota
Smart & Biggar
LandOfFree
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