Process for the production of cyclopropanenitrile derivatives

Details Process for the production of cyclopropanenitrile derivatives Process for the production of cyclopropanenitrile derivatives

C - Chemistry, Metallurgy

07

C

C07C 253/16 (2006.01) C07C 255/45 (2006.01) C07C 255/47 (2006.01) C07C 255/48 (2006.01) C07D 327/10 (2006.01)

Patent

CA 2057987

A process is disclosed for the production of cyclopropanenitrile derivatives, in which a diol of the formula: (see formula I) wherein R1 and R2 are the same or different and each is a hydrogen atom, a branched or unbranched C1-C6 alkyl group, or a branched or unbranched C1-C6 alkenyl group, or wherein R1 and R2 together form a C4-C6 cycloalkyl ring, is converted with thionyl chloride to form a compound of the formula: (see formula II) The latter compound is then oxidized to form a compound of the formula: (see formula III) The formula IV compound is subsequently converted with a cyano compound to form the desired end product of the formula: (See formula IV) wherein R1 and R2 have the above-mentioned meaning.

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