Mass spectrometric detection of polypeptides

G - Physics – 01 – N

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G01N 33/68 (2006.01)

Patent

CA 2300356

A process for determining the identity of a target polypeptide using mass spectroscopy is provided. Depending on the target polypeptide to be identified, a process as disclosed can be used, for example, to diagnose a genetic disease or chromosomal abnormality, a predisposition to a disease or condition, or infection by a pathogenic organism; or for determining identity or heredity. Kits for performing the disclosed processes also are provided.

L'invention se rapporte à un procédé de détermination de l'identité d'un polypeptide cible par spectroscopie de masse. Suivant le polypeptide cible à identifier, un tel procédé peut servir à diagnostiquer une maladie génétique ou une anomalie chromosomique, une prédisposition à une maladie ou une infection par un organisme pathogène. Ce procédé peut également servir à déterminer une identité ou une hérédité. L'invention se rapporte également à des trousses conçues pour la mise en oeuvre de ce procédé.

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