Method of treatment using steroid mouthwash

A - Human Necessities – 61 – K

Patent

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A61K 31/56 (2006.01) A61K 31/57 (2006.01) A61K 31/58 (2006.01) A61K 7/16 (1995.01)

Patent

CA 2103351

The object of the present invention is to provide a means of treating patients suffering from inflammatory conditions of the mouth using aqueous anti-inflammatory steroids in solutions that can be swished and expectorated as a mouthwash. Such therapy would allow direct contact of the medication with the diseased mucous membranes and would contact areas of the oral cavity that would not usually be reached with application of creams, gels, or ointments. Swishing for three to five minutes, then expectorating the aqueous anti-inflammatory-containing, results in maintenance of contact of the active agents with the oral cavity surfaces for a longer time than would application of gels containing those agents. The mode of application is simple and is not repugnant to the patient as is the application of creams, gels or ointments.

Cette invention concerne un proc'd' permettant de traiter des patients souffrant de pathologies inflammatoires de la cavit' buccale, . l'aide de st'ro<des anti-inflammatoires aqueux contenus dans des solutions avec lesquelles on peut se rincer la bouche et qu'on peut ensuite recracher, telles que des bains de bouche. Ce type de th'rapie permet de mettre directement en contact le m'dicament et les membranes malades de la muqueuse et d'atteindre des zones de la cavit' buccale qu'on ne peut g'n'ralement pas atteindre lorsqu'on applique une crSme, un gel ou une pommade. En se rin¸ant la bouche pendant trois . cinq minutes puis en recrachant le bain de bouche aqueux contenant des st'ro<des anti-inflammatoires, on fait rester les agents actifs plus longtemps en contact avec la muqueuse de la cavit' buccale que lorsqu'on applique un gel renfermant ces m¬mes agents. Ce mode d'application est simple et ne provoque pas de r'pugnance de la part des patients comme c'est le cas lorsqu'il s'agit d'appliquer une crSme, un gel ou une pommade.

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