C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 7/00 (2006.01) A61K 48/00 (2006.01) C12N 15/86 (2006.01) C12N 15/867 (2006.01)
Patent
CA 2280275
The present invention comprises spumavirus isolated from humans. More specifically, the spumavirus of the present invention was isolated from humans who had exposure to nonhuman primates. Importantly, the spumavirus of the present invention or antibodies to the spumavirus can be used to detect the presence of spumavirus or antibodies in body fluids, for pathogenicity studies of related viruses, and as a vector for gene therapies. The spumavirus of the invention can also be used for treatment of conditions in humans due to the presence of rapidly dividing cells and for recombinant live virus vaccination.
La présente invention concerne un spumavirus isolé d'origine humaine. Plus spécifiquement, le spumavirus de la présente invention a été isolé chez des êtres humains qui ont été en contact avec des primates non humains. De façon essentielle, le spumavirus de la présente invention ou des anticorps contre le spumavirus peuvent être utilisés pour détecter la présence de spumavirus ou d'anticorps dans des fluides corporels, en vue d'études de pathogénicité de virus apparentés, et comme vecteur pour des thérapies géniques. Le spumavirus de l'invention peut également être utilisé pour traiter des affections chez l'homme, provoquées par la présence de cellules se divisant rapidement, et pour des vaccinations à virus vivant recombiné.
Brown Jennifer
Folks Thomas M.
Heneine Walid
Sandstrom Paul A.
Switzer William M.
Department Of Health And Human Services The Government Of The United States Of America Represented By Th
Finlayson & Singlehurst
LandOfFree
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