A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/00 (2006.01) A61P 5/30 (2006.01) A61P 5/32 (2006.01) A61P 25/18 (2006.01) C12Q 1/68 (2006.01) G01N 33/92 (2006.01)
Patent
CA 2724332
Molecular signature for antipsychotics and SERMs has been identified, namely their upregulation of genes that alter lipid homeostasis, preferably of one or more of the following genes TNSIG1, SCD, FADS2, LDLR, FDPS, ACAT2, FDFT1, CYP51A1, FASN, DHCR7, RAB26, TM7SF2, SATB1, FAM117, GPNMB, NUPR1, VAC14, and LSS.
La présente invention concerne le fait que les signatures moléculaires indiquent une activité pharmacologique.
Lavedan Christian
Licamele Louis
Polymeropoulos Mihael H.
Shapiro Cohen
Vanda Pharmaceuticals Inc.
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