A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) A61K 51/08 (2006.01) A61K 51/10 (2006.01) C07K 16/00 (2006.01) C07K 16/30 (2006.01) C07K 16/44 (2006.01)
Patent
CA 2442839
The present invention relates to a bi-specific antibody or antibody fragment having at least one arm that is reactive against a targeted tissue and at least one other arm that is reactive against a linker moiety. The linker moiety encompasses a hapten to which antibodies have been prepared. The antigenic linker is conjugated to one or more therapeutic or diagnostic agents or enzymes. The invention provides constructs and methods for producing the bi- specific antibodies or antibody fragments, as well as methods for using them.
La présente invention concerne un anticorps bispécifique ou un fragment d'anticorps possédant au moins un bras réagissant contre un tissu ciblé et au moins un bras réagissant contre une fraction de liaison. Cette fraction de liaison comprend un haptène sur lequel des anticorps ont été préparés. Le lieur antigénique est conjugué avec un ou plusieurs agents ou enzymes thérapeutiques ou diagnostiques. L'invention se rapporte en outre à des constructions et à des méthodes permettant de produire ces anticorps bispécifiques ou ces fragments d'anticorps, ainsi qu'à leurs méthodes d'utilisation.
Goldenberg David M.
Griffiths Gary L.
Hansen Hans J.
Leung Shui-On
Mcbride William J.
Immunomedics Inc.
Smart & Biggar
LandOfFree
Production and use of novel peptide-based agents for use... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Production and use of novel peptide-based agents for use..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Production and use of novel peptide-based agents for use... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1536379