Formulations for therapeutic viruses having enhanced storage...

Details Formulations for therapeutic viruses having enhanced storage... Formulations for therapeutic viruses having enhanced storage...

C - Chemistry, Metallurgy

12

N

C12N 15/63 (2006.01)

Patent

CA 2599600

Therapeutic viral formulations having enhanced storage stability are described. The formulations comprise a viral vector in addition to one or more of an aqueous cosolvent, a reversible viral-encoded protease inhibitor and a mild reducing agent or other agent that prevents specific degradation of viral components.

La présente invention décrit des formulations virales thérapeutiques possédant une stabilité d'entreposage améliorée. Les formulations comprennent un vecteur viral en plus d~un ou plusieurs parmi un cosolvant aqueux, un inhibiteur de protéase à codage viral réversible, un faible agent réducteur ou autre agent qui empêche la dégradation spécifique des composants viraux.

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