Vaccines containing bordetella pertussis antigen

Details Vaccines containing bordetella pertussis antigen Vaccines containing bordetella pertussis antigen

A - Human Necessities

61

K

A61K 39/00 (2006.01) A61K 39/095 (2006.01) A61K 39/10 (2006.01) A61K 39/116 (2006.01)

Patent

CA 2294348

A vaccinating conjugate comprises an antigen conjugated to a carrier selected from Bordetella pertussis fimbria, pertussis toxin, pertussis toxoid, and pertussis 69kD protein. The conjugate may also comprise a second antigen, different from the first. An oral vaccinating composition comprises Bordetella pertussis fimbria or fimbria-antigen conjugate.

L'invention concerne un conjugué de vaccination qui comprend un antigène conjugué à un support sélectionné entre la fimbria de Bordetella pertussis, la toxine de la coqueluche, l'anatoxine de coqueluche et la protéine 69kD de la coqueluche. Le conjugué peut aussi renfermer un second antigène, différent du premier. Une composition orale de vaccination comprend une fimbria de Bordetella pertussis ou un conjugué fimbria-antigène.

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