Sample holder for dynamic light scattering

Details Sample holder for dynamic light scattering Sample holder for dynamic light scattering

G - Physics

01

N

G01N 21/01 (2006.01) G01N 1/42 (2006.01) G01N 1/44 (2006.01) G01N 15/02 (2006.01) G01N 33/49 (2006.01)

Patent

CA 2618852

A sample holder holds capillaries or cuvettes for use in dynamic light scattering (DLS) or quasi-elastic light scattering (QELS), such as in DLS of fluid samples such as platelet solutions, whole blood, colloids or the like. The sample holder has a base with a stationary backing member and a sliding, rail-mounted clamping member that is magnetically biased toward the backing member. The sample holder has Peltier-type thermoelectric heating/cooling elements that extend the full height of the clamping and backing members to optimize heat transfer efficiency. The sample holder further includes horizontal slots that enable collection of scattered light from various angles around the device. Finned heat sinks are mounted above and below the horizontal slots on the outwardly facing surfaces of the backing and clamping members to stabilize the temperature of the fluid sample in the sample holder without interfering with incident or scattered light.

Support d~échantillon contenant des capillaires ou des cuvettes pour utilisation dans la dispersion de lumière dynamique (DLS) ou la dispersion de lumière quasi élastique (QELS), comme dans le DLS d~échantillons de fluide comme des solutions de plaquettes, du sang total, des colloïdes et autres. Le support d~échantillon possède un socle avec un élément de renfort stationnaire et un élément de serrage coulissant monté sur rail polarisé magnétiquement vers l~élément de renfort. Le support d~échantillon possède des éléments de chauffage/de refroidissement thermoélectriques de type Peltier qui s~étendent sur toute la hauteur des éléments de serrage et de renfort pour optimiser l~efficacité du transfert thermique. Le support d~échantillon comporte en outre des fentes horizontales qui permettent de recueillir la lumière dispersée de divers angles autour du dispositif. Des dissipateurs de chaleur à ailettes sont montés au-dessus et au-dessous des fentes horizontales sur les surfaces dirigées vers l~extérieur des éléments de renfort et de serrage afin de stabiliser la température de l~échantillon de fluide dans le support d~échantillon sans interférer avec la lumière incidente ou dispersée.

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