Selective peroxisome proliferator activated receptor modulators

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 235/20 (2006.01) A61K 31/192 (2006.01) A61P 3/10 (2006.01)

Patent

CA 2549008

The present invention is directed to a novel compound, its composition and use of a compound having a structural formula (I), or a pharmaceutically acceptable salt, solvate, hydrate or stereoisomers thereof, which is useful in treating or preventing disorders mediated by a peroxisome proliferator activated receptor (PPAR) such as syndrome X, type II diabetes, hyperglycemia, hyperlipidemia, obesity, coagaulopathy, hypertension, arteriosclerosis, and other disorders related to syndrome X and cardiovascular diseases.

L'invention concerne un nouveau composé, sa composition et l'utilisation d'un composé de formule (I), ou d'un sel pharmaceutiquement acceptable, d'un solvate, d'un hydrate ou de stéréoisomères de celui-ci, qui et utile pour traiter ou pour prévenir des troubles médiés par un récepteur activé par les proliférateurs de péroxysome (PPAR), notamment le syndrome X, les diabètes de type II, l'hyperglycémie, l'hyperlipidémie, l'obésité, la coagulopathie, l'hypertension, l'artériosclérose, et d'autres troubles associés au syndrome X et à des maladies cardio-vasculaires.

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