Synthesis of acylaminoalkenylene amides useful as substance...

Details Synthesis of acylaminoalkenylene amides useful as substance... Synthesis of acylaminoalkenylene amides useful as substance...

C - Chemistry, Metallurgy

07

D

C07D 223/12 (2006.01) A61K 31/55 (2006.01) A61P 11/00 (2006.01)

Patent

CA 2645362

A process for preparing compounds of formula (I) or a solvate or hydrate thereof, where R, R1, R2, R3 and R5 have the meanings as indicated in the specification. Such compounds are useful in the treatment of a number of conditions associated with substance P and neurokinin.

La présente invention concerne un procédé de synthèse de composés de formule (I) ou de solvates ou hydrates desdits composés, R, R1, R2, R3 et R5 ayant les valeurs définies dans la description de l'invention. De tels composés peuvent être employés dans le traitement de plusieurs états pathologiques associés à la substance P et à la neurokinine.

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