Composition alleviating pain, containing a non-narcotic...

A - Human Necessities – 61 – K

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A61K 45/08 (2006.01) A61K 31/485 (2006.01)

Patent

CA 2197463

The analgesic effectiveness of a non-narcotic analgesic such as an NSAID or acetaminophen is significantly enhanced by administering the NSAID or acetaminophen prior to, with or following the administration of an analgesia enhancer which is a nontoxic NMDA receptor blocker and/or a nontoxic substance that blocks at least one major intracellular consequence of NMDA recpetor activation.

Il est possible d'accroître sensiblement l'effet analgésique d'un analgésique non narcotique tel qu'un analgésique anti-inflamatoire non stéroïdien (AINS) ou l'acétominophène en les administrant avant, avec ou après un activateur d'analgésie pouvant être un agent bloquant le récepteur NMDA et/ou une substance non toxique qui bloque au moins une conséquence intracellulaire principale de l'activation du récepteur NMDA.

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