Use of feedback control for the continuous phasing of cell...

C - Chemistry – Metallurgy – 12 – N

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C12N 5/00 (2006.01) C12N 5/02 (2006.01)

Patent

CA 2026229

ABSTRACT OF THE DISCLOSURE The present invention concerns a method for culturing cells which comprises periodic addition of a growth limiting nutrient, the period of which is controlled by a feedback means. The feedback means of the present invention is based on monitoring respiration rate and/or limiting nutrient concentration and/or a by-product concentration.

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