Use of chitosans for the treatment of nail inflammatory...

A - Human Necessities – 61 – K

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A61K 31/722 (2006.01) A61K 45/06 (2006.01) A61P 17/00 (2006.01) A61P 17/06 (2006.01) A61P 17/12 (2006.01) A61P 17/14 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2676259

Chitosan-based nail formulations are useful to treat nail inflammatory diseases like psoriasis, atopic dermatitis and lichen planus. The chitosan is normally in the form of an amino-polysaccharide derivative, preferably water soluble, such as hydroxypropyl chitosan. The formulation may be a nail lacquer, a spray, a cream, an ointment, a gel, a lotion or a foam and may have a content in chitosan, chitosan derivative or a salt thereof from 0.1 to 25 wt.% with respect to the total weight of the formulation.

Des formulations pour ongles à base de chitosan sont utiles pour traiter des maladies inflammatoires des ongles comme le psoriasis, la dermatite atopique et le lichen plan. Le chitosan est normalement sous la forme d'un dérivé d'amino polysaccharide, de préférence hydrosoluble, tel que l'hydroxypropyl chitosan. La formulation peut être présentée sous la forme d'un vernis à ongles, d'une pulvérisation, d'une crème, d'une pommade, un gel, d'une lotion ou d'une mousse; sa teneur en chitosan, en dérivé de chitosan ou en un sel de ceux-ci peut être de 0,1 à 25 % en poids par rapport au poids total de la formulation.

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