A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/426 (2006.01) A61K 31/4725 (2006.01) A61P 13/10 (2006.01) A61P 43/00 (2006.01)
Patent
CA 2704298
[Problems] To provide a pharmaceutical composition which is useful as a therapeutic agent for overactive bladder. [Means for solution] A pharmaceutical composition comprising (R)-2-(2--aminothiazol-4-yl)-4'-{2-[(2-hydroxy-2- phenylethyl)amino]ethyl}acetanilide or a pharmaceutically acceptable salt thereof and (3R)-quinuclidin-3-yl (1S)-1-phenyl-1,2,3,4--tetrahydroisoquinoline-2-carboxylate or a pharmaceutically acceptable salt thereof, as active ingredients, in particular a pharmaceutical composition for improving various symptoms accompanying overactive bladder, such as urinary urgency, pollakiuria and/or urinary incontinence
La présente invention concerne une composition pharmaceutique utile en tant qu'agent thérapeutique pour une vessie hyperactive. La composition pharmaceutique contient du (R)-2-(2-aminothiazol-4-yl)-4'-{2-[(2-hydroxy-2-phényléthyl)amino]éthyl}acétanilide, ou un sel pharmaceutiquement acceptable de ce composé, et du (3R)-quinuclidin-3-yl-(1S)-1-phényl-1,2,3,4-tétrahydroisoquinoline-2-carboxylate, ou un sel pharmaceutiquement acceptable de celui-ci, en tant qu'ingrédients actifs et elle se révèle particulièrement utile pour améliorer les symptômes accompagnant une hyperactivité de la vessie telle qu'une urgence de miction, des mictions fréquentes et/ou une incontinence urinaire.
Ohtake Akiyoshi
Suzuki Masanori
Ukai Masashi
Astellas Pharma Inc.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
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