Method of treatment, prophylaxis and diagnosis of...

A - Human Necessities – 61 – K

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A61K 48/00 (2006.01) A61K 39/395 (2006.01) A61P 19/08 (2006.01) A61P 19/10 (2006.01) A61P 35/04 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2637350

The present invention relates generally to the fields of treatment, prophylaxis and diagnosis. More particularly, the present invention identifies genes and gene products associated with bone morphogenesis and pathologies of the bone. Even more particularly, the present invention contemplates the regulation of expression of these genes or the activity of the gene products in the treatment, prophylaxis and diagnosis of bone pathologies. Cell-based therapies and manipulation of cells in in vitro culture also form part of the present invention.

La présente invention concerne les domaines du traitement, de la prophylaxie et du diagnostic en général. Plus particulièrement, la présente invention permet d~identifier des gènes et des produits de gènes associés à une morphogenèse osseuse et à des pathologies osseuses. Encore plus particulièrement, la présente invention concerne la régulation de l'expression de ces gènes ou de l'activité des produits de gènes dans le traitement, la prophylaxie et le diagnostic de pathologies osseuses. Des thérapies à base de cellules et des manipulations de cellules en culture in vitro font aussi partie de la présente invention.

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