Clinical test for detection of alzheimer's disease

Details Clinical test for detection of alzheimer's disease Clinical test for detection of alzheimer's disease

G - Physics

01

N

G01N 33/577 (2006.01) G01N 33/561 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2139333

A clinical method for the detection of Alzheimer's disease in living patients tests cerebrospinal fluid obtained from the pa- tient. The cerebrospinal fluid is tested using a Western blot analysis to determine reactivity with a polyclonal or a monoclonal an- tibody. The antibody is one which reacts with a broad band of immunoreactivity obtained upon separation of Alzheimer's specif- ic, material derived from filaments obtained from brains of deceased individuals having Alzheimer's disease. The test is particu- larly selective and enables one to identify patients with Alzheimer's disease and distinguishes these from patient's with other neurological disorders with similar symptoms such as Parkinson's disease and Pick's disease.

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