Benzoxazine derivatives as 5-ht6 modulators and uses thereof

C - Chemistry – Metallurgy – 07 – D

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C07D 413/04 (2006.01) A61K 31/536 (2006.01) A61P 25/18 (2006.01) C07D 265/36 (2006.01) C07D 267/14 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2485136

The present invention provides a compound which has 5-HT6receptor affinity of the formula (I): a pharmaceutically acceptable salt or a prodrug thereof, where R1, R2, R3, R4, R5, R6, R7, R8, R9, Y, Z1, m, n, and p are as defined herein. The present invention also provides compositions comprising, methods for using, and methods for preparing Compound of Formula (I).

La présente invention concerne un composé de formule (I) qui présente une affinité de récepteur de 5-HT6, un sel ou un promédicament de celui-ci, acceptables d'un point de vue pharmaceutique. Dans la formule (I), R?1¿, R?2¿, R?3¿, R?4¿, R?5¿, R?6¿, R?7¿, R?8¿, R?9¿, Y, Z?1¿, m, n, et p sont tels que définis dans cette invention. La présente invention concerne également des compositions comprenant ledit composé de formule (I), des procédés pour l'utiliser et des procédés pour le préparer.

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