Liquid dosage forms of proton pump inhibitors

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/4439 (2006.01) A61K 9/00 (2006.01) A61K 9/08 (2006.01) A61P 1/04 (2006.01)

Patent

CA 2490142

Provided herein are pharmaceutical formulations comprising micro-granules and a liquid suspension vehicle having a pH less than 6.0 and a viscosity sufficient to suspend the micro-granules. The micro-granules typically contain a PPI which therefore makes the above formulation, as well as kits for making the above formulation, useful for alleviating the symptoms of gastrointestinal disorders or diseases.

L'invention concerne des formulations pharmaceutiques comprenant des micro-granulés et un excipient liquide en suspension présentant un pH inférieur à 5,0 et une viscosité suffisante pour mettre lesdits micro-granulés en suspension. Lesdits micro-granulés contiennent généralement un IPP (inhibiteur de la pompe à protons) qui contribue de ce fait à la production de ladite formulation. L'invention concerne également des kits de production de ladite formulation servant à alléger les symptômes de troubles gastro-intestinaux ou de maladies associées.

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