Naphthyridinones for inhibiting protein tyrosine kinase and...

Details Naphthyridinones for inhibiting protein tyrosine kinase and... Naphthyridinones for inhibiting protein tyrosine kinase and...

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/44 (2006.01)

Patent

CA 2291222

Naphthyridinones of Formula (I) are inhibitors of PTKs and cell cycle kinases, and are useful in treating cellular proliferation. The compounds are especially useful in treating cancer, atherosclerosis, restenosis, and psoriasis.

L'invention concerne des naphtyridinones représentées par la formule (I), qui constituent des inhibiteurs de la protéine tyrosine kinase (PTK) et de kinases de cycle cellulaire, et qui sont utiles pour traiter une prolifération cellulaire. Ces composés sont particulièrement utiles dans le traitement de cancer, d'athérosclérose, de resténose et de psoriasis.

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