Magnetic resonance imaging agents for the delivery of...

Details Magnetic resonance imaging agents for the delivery of... Magnetic resonance imaging agents for the delivery of...

A - Human Necessities

61

K

A61K 49/10 (2006.01) A61K 41/00 (2006.01)

Patent

CA 2307332

The invention relates to magnetic resonance imaging contrast agents that report on physiological events in a conditional fashion and simultaneously detect the delivery and/or activation of a therapeutically active agent. The agents are of the following formulae: (see formula I) (see formula II) wherein the linker is an unsubstituted or substituted group selected from alkylene, arylene and hetero arylene groups, and (see formula III).

L'invention se rapporte à de nouveaux agents de contraste pour imagerie par résonance magnétique qui servent à signaler de manière conditionnelle des événements physiologiques et à détecter en même temps l'apport et/ou l'activation d'un agent thérapeutiquement actif.

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