Extracellular matrix polynucleotides, polypeptides, and...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/12 (2006.01) A61K 31/7088 (2006.01) A61K 31/713 (2006.01) A61K 38/00 (2006.01) A61K 38/17 (2006.01) A61K 38/47 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) A61P 7/04 (2006.01) A61P 9/10 (2006.01) A61P 17/00 (2006.01) A61P 17/02 (2006.01) A61P 19/02 (2006.01) A61P 19/10 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) C07H 21/04 (2006.01) C07K 14/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C07K 16/40 (2006.01) C12N 1/15 (2006.01) C12N 1/19 (2006.01) C12N 1/21 (2006.01) C12N 5/10

Patent

CA 2403508

The present invention relates to novel human ECM polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human ECM polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel humam ECM polypeptides.

L'invention concerne des nouveaux polypeptides matriciels extracellulaires humains et des acides nucléiques isolés contenant les régions codantes des gènes codant pour de tels polypeptides. Elle concerne également des vecteurs, cellules hôtes, anticorps et procédés de recombinaison servant à produire ces polypeptides matriciels extracellulaires humains, de même que des méthodes diagnostiques et thérapeutiques, utiles pour diagnostiquer et traiter des troubles associés à ces nouveaux polypeptides matriciels extracellulaires humains.

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