Methods of transducing neural cells using lentivirus vectors

Details Methods of transducing neural cells using lentivirus vectors Methods of transducing neural cells using lentivirus vectors

A - Human Necessities

61

K

A61K 48/00 (2006.01) A61P 25/14 (2006.01) A61P 25/16 (2006.01) A61P 25/28 (2006.01) C12N 15/86 (2006.01) C12N 15/867 (2006.01)

Patent

CA 2410015

Gene delivery vectors, such as, for example, recombinant FIV vectors, and methods of using such vectors are provided for use in transducing neural cells, such as neural progenitor cells, and cerebellar neurons, in particular, Purkinje cells.

L'invention concerne des vecteurs pour l'acheminement de gènes, comme les vecteurs de recombinaison du virus d'immunodéficience féline. L'invention concerne également des procédés relatifs à l'utilisation de ces vecteurs pour la transduction des cellules neuronales, comme les cellules neuronales du type progéniteur, et des neurones cérébelleux, en particulier les cellules de Purkinje.

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