C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 233/78 (2006.01) A61K 31/165 (2006.01) A61K 31/17 (2006.01) A61K 31/36 (2006.01) A61K 31/44 (2006.01) A61K 45/06 (2006.01) A61P 33/06 (2006.01) C07C 211/27 (2006.01) C07C 217/58 (2006.01) C07C 235/50 (2006.01) C07C 255/58 (2006.01) C07C 255/60 (2006.01) C07C 275/28 (2006.01) C07C 275/32 (2006.01) C07D 213/38 (2006.01) C07D 239/26 (2006.01) C07D 317/58 (2006.01)
Patent
CA 2428266
The invention relates to novel compounds which are substituted alkyldiamino derivatives of formula (I). The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more compounds of formula (I) and especially their use as inhibitors of the plasmodium falciparum protease plasmepsin II or related aspartic proteases.
L'invention porte sur de nouveaux composés qui sont des dérivés alkyldiamino substitués de la formule (I). L'invention porte également sur des procédés de préparation des composés, sur des compositions pharmaceutiques contenant un ou plusieurs composés de la formule (I) et notamment sur leur utilisation comme inhibiteurs de plasmodium falciparum protéase plasmepsine II ou des protéases aspartiques apparentées.
Boss Christoph
Fischli Walter
Meyer Solange
Richard-Bildstein Sylvia
Weller Thomas
Actelion Pharmaceuticals Ltd.
Gowling Lafleur Henderson Llp
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