C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 263/48 (2006.01)
Patent
CA 2271197
The present invention relates to the production of pemoline (2-imino-5-phenyl- 4-oxazilidinone) and its intermediates, reacting a cyanamide containing compound in a sodium alkoxide solution to form a reaction mixture. The reaction mixture is then added to an alkyl mandelate-solvent solution. The resultant reaction mixture is then acidified to a pH of 6.0 or less to precipitate a pemoline product.
La présente invention concerne la production de pémoline (2-imino-5-phényl-4 oxyzolidinone) et de ses intermédiaires, par réaction d'un composé renfermant un cyanamide avec une solution d'alkoxyde de sodium, afin de former un mélange réactionnel. Ce mélange réactionnel est ensuite ajouté à une solution de solvant renfermant du mandélate d'alkyle. Le mélange réactionnel ainsi formé est ensuite acidifié à un pH inférieur ou égal à 6,0, de manière à précipiter un produit de pémoline.
Abbott Laboratories
Ogilvy Renault
LandOfFree
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