Process for producing edible orally administered agent of...

A - Human Necessities – 61 – J

Patent

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A61J 3/00 (2006.01) B29D 99/00 (2010.01) A23P 1/10 (2006.01) A61K 9/20 (2006.01) A61K 9/70 (2006.01)

Patent

CA 2504814

Two resin films each provided with an edible orally administered agent layer are joined together so that the administered agent layers face each other, drawn into interstice between a pair of press rolls whereby the resin films at back sides are pressurized so as to effect bonding of the administered agent layers, and conveyed forward in the direction nearly conforming to the tangent direction at the pressurization zone of press rolls. By means of stripping rolls disposed along the conveyance direction, only one of the two resin films having the mutually bonded plural administered agent layers interposed therebetween is drawn in a direction different from the conveyance direction while the other resin film retaining the plural administered agent layers is continuously conveyed in the conveyance direction. Thus, only one of the two resin films joined together is detached. The obtained compression bonding product, i.e., edible orally administered agent of laminate film form can be punched into given shapes.

L'invention concerne deux films de résine comportant chacun une couche d'agent comestible aux fins d'administration par voie orale, assemblés de sorte que lesdites couches soient face à face, étirés dans l'interstice entre une paire de rouleaux de compression pour qu'une pression s'applique sur les faces de film arrière aux fins de liaison entre les couches, et acheminés vers l'avant dans la direction presque conforme à la tangente, au niveau de la zone de pression des rouleaux de compression. Des rouleaux de détachement placés dans le sens d'acheminement permettent d'étirer seulement un des deux films de résine entre lesquels se trouvent les couches considérées, dans une direction différente de la direction d'acheminement, tandis que l'autre film retenant lesdites couches est acheminé en continu dans la direction d'acheminement. Ainsi, seul un des deux films assemblés est détaché. Il en résulte un produit de liaison par compression, en l'occurrence un agent comestible pour administration par voie orale à configuration de film laminé, susceptible d'être poinçonné sous telle ou telle forme.

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