Method for the isolation and expansion of cardiac stem cells...

Details Method for the isolation and expansion of cardiac stem cells... Method for the isolation and expansion of cardiac stem cells...

C - Chemistry, Metallurgy

12

N

C12N 5/0775 (2010.01) C12N 5/074 (2010.01) C12N 5/077 (2010.01) A61K 35/34 (2006.01) A61P 9/00 (2006.01)

Patent

CA 2534378

Method for the isolation, expansion and preservation of cardiac stem cells from human or animal tissue biopsy samples to be employed in cell transplantation and functional repair of the myocardium or other organs. Cells may also be used in gene therapy for treating genetic cardiomyopathies, for treating ischemic heart diseases and for setting in vitro models to study drugs.

L'invention concerne une méthode permettant d'isoler, de développer et de préserver des cellules souches cardiaques à partir d'échantillons de biopsie de tissu humain ou animal à utiliser dans une transplantation cellulaire et pour une réparation fonctionnelle du myocarde ou d'autres organes. On peut également utiliser ces cellules en thérapie génique afin de traiter des cardiomyopathies génétiques et des cardiopathies ischémiques, et d'établir des modèles in vitro permettant d'étudier des médicaments.

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