Use of pyrimidylaminobenzamides for the treatment of...

A - Human Necessities – 61 – K

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A61K 31/506 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2594687

Abstract The present invention relates to the use of pyrimidylaminobenzamide compounds for the preparation of a drug for the treatment of diseases that respond to modulation of kinase, especially tie-2 kinase, activity, especially for the curative and/or prophylactic treatment of leukemia, myelodysplastic syndromes or pulmonary hypertension, and to a method of treating diseases that respond to modulation of kinase activity, especially tie-2 kinase activity.

La présente invention concerne l'utilisation de composé pyrimidylaminobenzamide pour la préparation de médicaments destinés au traitement de maladies qui répondent à la modulation de kinase, en particulier de l'activité tie-2 kinase, et plus particulièrement pour le traitement curatif et prophylactique de la leucémie, des syndromes myélodysplasiques ou de l'hypertension pulmonaire et, une technique de traitement de maladies qui répondent à la modulation de l'activité kinase, en particulier de l'activité tie-2 kinase

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