A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/118 (2006.01) A61K 38/16 (2006.01) A61P 31/04 (2006.01) A61P 37/04 (2006.01) C12Q 1/68 (2006.01) G01N 33/571 (2006.01) C07K 14/295 (2006.01) C12N 15/31 (2006.01)
Patent
CA 2418282
Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
L'invention concerne des composés et méthodes de diagnostic et de traitement de l'infection à Chlamydia. Ces composés contiennent des polypeptides ayant au moins une partie antigénique d'un antigène de genre Chlamydia et des séquences d'ADN codant pour lesdits polypeptides. L'invention concerne également des compositions pharmaceutiques et des vaccins contenant lesdits polypeptides ou séquences d'ADN ainsi que des anticorps dirigés contre ces polypeptides. Des kits de diagnostic contenant ces polypeptides ou séquences d'ADN et un réactif de détection approprié peuvent être utilisés pour détecter l'infection à Chlamydia chez des patients et dans des échantillons biologiques.
Bhatia Ajay
Fling Steven P.
Probst Peter
Skeiky Yasir A. W.
Corixa Corporation
Gowling Lafleur Henderson Llp
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