Protein biomaterials and biocoacervates and methods of...

A - Human Necessities – 61 – L

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A61L 27/54 (2006.01) A61K 45/06 (2006.01) A61K 47/36 (2006.01) A61K 47/42 (2006.01) A61L 15/32 (2006.01) A61L 29/16 (2006.01) A61L 31/16 (2006.01) A61P 17/02 (2006.01)

Patent

CA 2537315

The present invention relates to protein biocoacervates and biomaterials and the methods of making and using protein biocoacervates and biomaterials. More specifically the present invention relates to protein biocoacervates and biomaterials that may be utilized for various medical applications including, but not limited to, drug delivery devices for the controlled release of pharmacologically active agents, coated medical devices (e.g. stents, valves ... ), vessels, tubular grafts, vascular grafts, wound healing devices including protein suture biomaterials and biomeshes, dental plugs and implants, skin/bone/tissue grafts, tissue fillers, protein biomaterial adhesion prevention barriers, cell scaffolding and other biocompatible biocoacervate or biomaterial devices.

L'invention concerne des coacervats et des biomatériaux protéiniques et leurs procédés de fabrication et d'utilisation. L'invention porte plus spécifiquement sur des coacervats et des biomatériaux protéiniques pouvant être utilisés pour diverses applications médicales, dont, entre autres, des dispositifs de libération contrôlée de médicament pour la libération contrôlée d'agents actifs au plan pharmacologique, des dispositif médicaux enduits (ex. endoprothèses vasculaires, valvules), des vaisseaux, des greffons tubulaires, des greffons vasculaires, des dispositifs de cicatrisation comprenant des biomatériaux de suture protéiniques et des biotreillis, des bouchons et des implants dentaires, des greffons épidermiques/osseux/tissulaires, des barrières empêchant l'adhérence du biomatériau protéinique, un squelette cellulaire et un autre biocoacervat biocompatible ou d'autres dispositifs à biomatériaux.

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