Combination of a gaba-a alpha 5 inverse agonist and a...

A - Human Necessities – 61 – K

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A61K 31/50 (2006.01) A61K 31/14 (2006.01) A61K 31/42 (2006.01) A61K 31/445 (2006.01) A61K 31/465 (2006.01) A61K 31/495 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2324237

The present invention relates to a combination of a nicotinic agonist and an inverse agonist of the GABAA .alpha.5 receptor subtype, and the use of the combination in treating neurodegenerative conditions such as Alzheimer's Disease.

L'invention porte sur une combinaison d'un agoniste de la nicotine et d'un agoniste inverse du sous type .alpha.¿5? du récepteur GABA¿A? et sur l'utilisation de ladite combinaison pour le traitement de troubles de neurodégénerescence tels que la maladie d'Alzheimer.

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