Piperazine-alkyl-ureido derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 401/12 (2006.01) A61K 31/4709 (2006.01) A61K 31/497 (2006.01) A61P 9/10 (2006.01) A61P 9/12 (2006.01)

Patent

CA 2523566

The invention relates to novel piperazine derivatives and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as neurohormonal antagonists. (I)

L'invention concerne de nouveaux dérivés de pipérazine de formule (1) et des composés associés, ainsi que leur utilisation comme agents actifs dans la préparation de compositions pharmaceutiques. La présente invention porte également sur d'autres aspects tels que sur des procédés pour préparer ces composés, sur des compositions pharmaceutiques contenant un ou plusieurs de ces composés et surtout sur leur utilisation en tant qu'antagonistes neurohormonaux.

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