Novel crystals of 1,3,4-oxadiazole derivative, process for...

C - Chemistry – Metallurgy – 07 – D

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C07D 413/12 (2006.01) A61K 31/506 (2006.01) A61P 1/02 (2006.01) A61P 9/02 (2006.01) A61P 9/10 (2006.01) A61P 11/00 (2006.01) A61P 13/12 (2006.01) A61P 17/00 (2006.01) A61P 25/28 (2006.01) A61P 27/02 (2006.01) A61P 29/02 (2006.01) A61P 35/00 (2006.01) A61P 37/06 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2421499

Form 2 crystals of 2-[5-amino-6-oxo-2-phenyl-1,6-dihydro-1-pyrimidyl]-N-[1-(2- [5-t-butyl-1,3,4-oxadiazolyl]carbonyl)-2-R,S)-methylpropyl]acetamide (I); a process for producing the crystals; and medicines containing the same as the active ingredient.

La présente invention concerne d'une part des cristaux forme 2 de 2-[5-amino-6-oxo-2-phényl-1,6-dihydro-1-pyrimidyl]-N-[1-(2-[5-t-butyl-1,3,4-oxadiazolyl]carbonyl)-2-R,S)-méthylpropyl]acétamide (I), d'autre part un procédé de production de ces cristaux, en enfin des médicaments les intégrant comme principes actifs.

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