Indano pyrrolidine carbamates

Details Indano pyrrolidine carbamates Indano pyrrolidine carbamates

C - Chemistry, Metallurgy

07

D

C07D 209/70 (2006.01) A61K 31/40 (2006.01) A61K 31/41 (2006.01) A61K 31/44 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) C07D 401/02 (2006.01) C07D 403/02 (2006.01) C07D 405/02 (2006.01) C07D 409/02 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2086433

Disclosed in an indano-pyrrolidine compound useful in the treatment of Alzheimer's disease and is represented by the formula: (see formula I) wherein W is CR3R4 or CO; R1 is H, alkyl, alkenyl, phenyl or the like; R3 and R4 are H, alkyl, OH, halogen, amino or the like; R5, R6 and R8 are H, alkyl, phenyl or the like, R7 is OH, SH, O-alkyl, S-alkyl, OCONR13R14, SCONR13R14 or OCSNR13R14 (where R13 and R14 are H, alkyl, phenyl or the like; R9 is H, alkyl or the like, and R10 and R11 are H, alkyl, phenyl or benzyl.

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