Candidates against infection

Details Candidates against infection Candidates against infection

A - Human Necessities

61

K

A61K 38/48 (2006.01) A01K 67/027 (2006.01) A61K 38/36 (2006.01) A61P 31/00 (2006.01) A61P 31/04 (2006.01) G01N 33/00 (2006.01)

Patent

CA 2662101

The present invention relates to the use of plasminogen/plasmin and its derivatives as agents for enhancing host defense against infection or other infectious diseases. The invention also relates to a method for screening of compounds which enhance host defense against infection by evaluating the host defense against bacterial arthritis and spontaneous otitis media in an animal model.

L'invention concerne l'utilisation de plasminogène/plasmine et de ses dérivés comme agents de renforcement des défenses de l'organisme contre les infections ou autres maladies infectieuses. L'invention concerne également un procédé de criblage de composés qui renforcent les défenses de l'organisme contre les infections et qui consiste à évaluer les défenses de l'organisme contre l'arthrite bactérienne et de l'otite moyenne spontanée chez un modèle animal.

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