Drug delivery system by administrating fine particles to...

A - Human Necessities – 61 – K

Patent

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Details

A61K 47/30 (2006.01) A61K 31/573 (2006.01) A61K 31/58 (2006.01) A61P 7/00 (2006.01) A61P 27/02 (2006.01) A61P 29/00 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2536185

It is intended to provide a continuous drug delivery system targeting a tissue in the posterior segment of eye which needs no frequent administration and shows little tissue invasion. Namely, a drug delivery system whereby a drug is selectively transferred into the posterior segment of eye, thereby lessening effects of the drug transfer on the anterior segment of eye. By administering fine grains containing a drug under Tenon~s capsule, a drug delivery system ensuring the selective transfer of the drug toward the posterior segment of eye and maintenance of an efficacious drug concentration can be constructed.

La présente invention concerne un système d'administration continue de produit pharmaceutique qui cible un tissu situé dans le segment postérieur de l'oeil, qui permet d'éviter d'avoir recours à des administrations fréquentes et se caractérise par une faible invasion tissulaire. L'invention concerne notamment un système d'administration de produit pharmaceutique, un produit pharmaceutique étant transféré de manière sélective à l'intérieur du segment postérieur de l'oeil, ce qui permet de limiter les effets du transfert de produit pharmaceutique sur le segment antérieur de l'oeil. Grâce à l'administration de fins grains contenant un produit pharmaceutique, sous la capsule de Tenon, on obtient un système d'administration de produit pharmaceutique qui garantit le transfert sélectif du produit pharmaceutique vers le segment postérieur de l'oeil et la conservation d'une concentration efficace en produit pharmaceutique.

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