A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/425 (2006.01) A61K 31/415 (2006.01) A61K 31/4184 (2006.01) A61K 31/427 (2006.01)
Patent
CA 2223435
A pharmaceutical composition for the treatment of leukemia in mammals is disclosed. The particular fungicide used is a benzimidazole derivative of formula (I), wherein X is hydrogen, halogen, alkyl of less than 7 carbon atoms or alkoxy of less than 7 carbon atoms; n is a positive integer of less than 4; Y is hydrogen, chlorine, nitro, methyl or ethyl; and R is hydrogen or an alkyl group having from 1 to 8 carbon atoms, and R2 is 4-thiazolyl or NHCOOR1 wherein R1 is aliphatic hydrocarbon of less than 7 carbon atoms or the pharmaceutically acceptable inorganic or acid addition salts thereof.
On décrit une composition pharmaceutique destinée au traitement de la leucémie chez les mammifères. Le fongicide utilisé en particulier est un dérivé benzimidazole de la formule (I), ou des sels inorganiques ou d'addition d'acide de celui-ci, acceptables sur le plan pharmacologique. Dans cette formule, X représente hydrogène, halogène, alkyle possédant moins de 7 atomes de carbone, ou alcoxy possédant moins de 7 atomes de carbone; n est un nombre positif entier inférieur à 4; Y représente hydrogène, chlore, nitro, méthyle ou éthyle; R représente hydrogène ou un groupe alkyle possédant 1 à 8 atomes de carbone, et R¿2? représente 4-thiazolyle ou NHCOOR¿1? dans lequel R¿1? représente un hydrocarbure aliphatique possédant moins de 7 atomes de carbone.
Dimock Stratton Llp
The Procter & Gamble Company
LandOfFree
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