Reducing carbohydrate derivatives of adamantane amines, and...

Details Reducing carbohydrate derivatives of adamantane amines, and... Reducing carbohydrate derivatives of adamantane amines, and...

C - Chemistry, Metallurgy

07

C

C07C 211/38 (2006.01) A61K 31/133 (2006.01)

Patent

CA 2587595

The present invention relates to reducing carbohydrate derivatives of adamantane amines of Formula (A) or pharmaceutically acceptable salts, solvates or derivatives thereof, wherein R1, R2, R3, and R4 are together or separately H, F, methyl or lower alkyl, alkenyl, or alkynyl groups, and Z is derived from a mono-, di-, oligo-, or poly-saccharide that originally had an aldehyde carbonyl group. The present invention also relates to processes for the preparation of such adamantane amine derivatives, and uses of such derivatives. The compounds of the present invention are useful in the treatment of infections caused by Gram positive or Gram negative bacteria.

Cette invention porte sur la réduction de dérivés de carbohydrates d'amines d'adamantane de formule (A) ou de ses sels, solvates ou dérivés pharmaceutiquement acceptables, dans laquelle R1, R2, R3, et R4 représentent ensemble ou séparément H, F, des groupes de méthyle ou d'alkyle inférieur, d'alcényle ou d'alkynyle et dans laquelle Z est dérivée d'un mono-, di-, oligo-, ou poly-saccharide qui avait au départ un groupe aldéhyde carbonyle. Cette invention concerne également des procédés de préparation desdits dérivés d'amine d'adamantane et l'utilisation de ces dérivés. Les composés décrits dans l'invention sont utiles pour le traitement d'infections causées par des bactéries gram positives ou gram négatives.

Affiliated with

Also associated with

Rating

Reducing carbohydrate derivatives of adamantane amines, and... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Reducing carbohydrate derivatives of adamantane amines, and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Reducing carbohydrate derivatives of adamantane amines, and... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1552492